In 2020, the Global Partnership launched a guidance document that reviewed the latest evidence on effective programmes to eliminate HIV-related stigma and discrimination in the six settings of the Global Partnership. The present guidance is a companion to the evidence guidance focused on monitoring and evaluation, with the goal of supporting programme planners, implementers and managers at government agencies and nongovernmental and community-based organizations to understand the outputs and outcomes of their programmes and inform programme improvement and scale-up. This document is also available in Portuguese.