The meeting—titled Cities Ending the AIDS Epidemic—was the first in a week-long series of side events and panels in support of the UN General Assembly High-Level Meeting on Ending AIDS. The High-Level Meeting culminated in an agreement on a 2016 Political Declaration on HIV and AIDS, which provides specific, time-bound targets and actions to get the world on the Fast-Track to ending the AIDS epidemic. The targets and commitments of the 2016 Political Declaration will guide the world in addressing the critical linkages between health, development, social justice, inequality, poverty and conflict. This document summarizes the proceedings of the meeting on 6 June and related events on 7 June.