Launched only a year ago, Fast-Track cities has rapidly taken root and grown. This is the first annual update on progress in implementing the Fast-Track cities approach and it supports one of the seven key commitments contained in the Paris Declaration. This report reflects on the actions taken by cities and by the four core partners— the city of Paris, UNAIDS, the United Nations Human Settlements Programme (UN-Habitat) and the International Association of Providers of AIDS Care (IAPAC)—towards ending the AIDS epidemic as a public health threat by 2030. Future reports will illustrate good practices and quantifiable evidence of progress that will inspire and inform Fast-Track cities and the many stakeholders helping to confront AIDS as a health and development challenge.