In Thailand, too many girls find themselves at an early age in the sex industry, usually for lack of other options for earning a living. Young girls are desirable because they are thought to be “safe” and uninfected with HIV, but the risk of infection to them, and thence to their clients, is very high. This case study describes some responses to that problem, focusing on changing the attitudes of girls and their parents in regard to prostitution, and on providing a means for girls to avoid becoming sex workers through improved education and career opportunities.