This case study examines the Global Strategy Framework--a set of guiding principles and leadership commitments that form the basis of a successful response to the epidemic. It aims to support communities and countries in reducing their risk and vulnerability to infection, save lives and alleviate human suffering, and lesson the epidemic’s impact on development. It also calls for profound changes in the conduct of community, national and international affairs. The Global Strategy Framework is not a detailed blueprint, so global, national, and community bodies will still need to formulate their own specific strategies concerning particular themes or regions. At the core of the Strategy stands the conviction that tackling the epidemic is an indisputable, global priority, and that an expanded, extraordinary response is not simply necessary, but feasible.